Prevalence and Factors Associated with Coronary Artery Disease (CAD) and Its Associated Factors among People Aged 35 Years and Over in Thailand: A Cross-Sectional Analysis




Coronary artery disease (CAD), Modifiable risk factors, People aged 35 years and over


Background: Coronary artery disease (CAD) is a significant public health problem. CAD remains the leading cause of death worldwide, estimated 85% occurring in low-income and middle-income countries, and act as the number one cause of death in all ages and from all races. While CAD is a significant cause of death and disability, it is preventable.
Objectives: The aim of this study was to assess the prevalence and factors associated with CAD among people aged 35 years and over in Thailand.
Methods: The data for this cross-sectional study was extracted from the Health Data Center (HDC) of Thailand's Ministry of Public Health between 2016-2021 were used. The outcome, defined as having CAD diagnosed previously by a physician. This study comprised a total of 128,065 participants who matched the HDC inclusion criteria. Generalized linear mixed model (GLMM) analysis was used to assess independent factors associated with CAD among people aged 35 years and over.
Results: Records of 128,065 participants were included for analysis. The prevalence of CAD among people aged 35 years and over were 30.83% (95%CI=30.57-31.08). In GLMM analysis, being female (Adj.OR=2.57, 95%CI=2.48-2.66), 60 years and higher (Adj.OR=3.22, 95%CI=2.99-3.46), alcohol regularly (Adj.OR=2.74, 95%CI=2.61-2.87), family history of DM (Adj.OR=2.71, 95%CI=2.61-2.82), obesity (≥25 kg/m2) (Adj.OR= 3.62, 95%CI=3.26-4.02), high blood pressure (>140/>90 mmHg) (Adj.OR= 5.34, 95%CI=5.11-5.58), high FBS (≥126 mg/dL) (Adj.OR= 1.53, 95%CI=1.48-1.58), high LDL (>100 mg/dL)(Adj.OR=7.11, 95%CI=6.84-7.38), low HDL (<40 mg/dL) (Adj.OR=3.69, 95%CI=3.55-3.82), eGFR stage 2 (moderate loss of kidney function) (<60 ml/min/ 1.73 m2) (Adj.OR=2.32, 95%CI=2.22-2.42)
Conclusion: Results of the present research showed that, there is a significant relationship between modifiable risk factors of CAD. The findings of this study will benefit public sectors or related organizations and policymakers’ developers to develop efficient measures to control factors of CAD among people aged 35 years and over in the country.

Author Biographies

  • Chutian Sakphisutthikul, Faculty of Public Health, Khon Kaen University



  • Wongsa Laohasiriwong, Faculty of Public Health, Khon Kaen University



  • Roshan Kumar Mahato, Faculty of Public Health, Khon Kaen University



  • Krittiyanee Thammasarn, Faculty of Public Health, Khon Kaen University




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Original Article


How to Cite

Prevalence and Factors Associated with Coronary Artery Disease (CAD) and Its Associated Factors among People Aged 35 Years and Over in Thailand: A Cross-Sectional Analysis. IJPHAP [Internet]. 2022 Dec. 1 [cited 2024 Jun. 20];1(1). Available from: