Prevalence and Factors Associated with Coronary Artery Disease (CAD) and Its Associated Factors among People Aged 35 Years and Over in Thailand: A Cross-Sectional Analysis

Authors

DOI:

https://doi.org/10.62992/ijphap.v1i1.16

Keywords:

Coronary artery disease (CAD), Modifiable risk factors, People aged 35 years and over

Abstract

Background: Coronary artery disease (CAD) is a significant public health problem. CAD remains the leading cause of death worldwide, estimated 85% occurring in low-income and middle-income countries, and act as the number one cause of death in all ages and from all races. While CAD is a significant cause of death and disability, it is preventable.
Objectives: The aim of this study was to assess the prevalence and factors associated with CAD among people aged 35 years and over in Thailand.
Methods: The data for this cross-sectional study was extracted from the Health Data Center (HDC) of Thailand's Ministry of Public Health between 2016-2021 were used. The outcome, defined as having CAD diagnosed previously by a physician. This study comprised a total of 128,065 participants who matched the HDC inclusion criteria. Generalized linear mixed model (GLMM) analysis was used to assess independent factors associated with CAD among people aged 35 years and over.
Results: Records of 128,065 participants were included for analysis. The prevalence of CAD among people aged 35 years and over were 30.83% (95%CI=30.57-31.08). In GLMM analysis, being female (Adj.OR=2.57, 95%CI=2.48-2.66), 60 years and higher (Adj.OR=3.22, 95%CI=2.99-3.46), alcohol regularly (Adj.OR=2.74, 95%CI=2.61-2.87), family history of DM (Adj.OR=2.71, 95%CI=2.61-2.82), obesity (≥25 kg/m2) (Adj.OR= 3.62, 95%CI=3.26-4.02), high blood pressure (>140/>90 mmHg) (Adj.OR= 5.34, 95%CI=5.11-5.58), high FBS (≥126 mg/dL) (Adj.OR= 1.53, 95%CI=1.48-1.58), high LDL (>100 mg/dL)(Adj.OR=7.11, 95%CI=6.84-7.38), low HDL (<40 mg/dL) (Adj.OR=3.69, 95%CI=3.55-3.82), eGFR stage 2 (moderate loss of kidney function) (<60 ml/min/ 1.73 m2) (Adj.OR=2.32, 95%CI=2.22-2.42)
Conclusion: Results of the present research showed that, there is a significant relationship between modifiable risk factors of CAD. The findings of this study will benefit public sectors or related organizations and policymakers’ developers to develop efficient measures to control factors of CAD among people aged 35 years and over in the country.

Author Biographies

  • Chutian Sakphisutthikul, Faculty of Public Health, Khon Kaen University

     

     

  • Wongsa Laohasiriwong, Faculty of Public Health, Khon Kaen University

     

     

  • Roshan Kumar Mahato, Faculty of Public Health, Khon Kaen University

     

     

  • Krittiyanee Thammasarn, Faculty of Public Health, Khon Kaen University

     

     

References

Organization WH. World health statistics 2016: monitoring health for the SDGs sustainable development goals: World Health Organization; 2016.

Benjamin EJ, Muntner P, Alonso A, Bittencourt MS, Callaway CW, Carson AP, et al. Heart disease and stroke statistics—2019 update: a report from the American Heart Association. 2019;139(10):e56-e528,

Organization WH. Global status report on alcohol and health 2018: World Health Organization; 2019.

Baharudin N, Mohamed-Yassin M-S, Daher AM, Ramli AS, Khan N-AMN, Abdul-Razak SJBph. Prevalence and factors associated with lipid-lowering medications use for primary and secondary prevention of cardiovascular diseases among Malaysians: the REDISCOVER study. 2022;22(1):1-12,

Hosmer Jr DW, Lemeshow S, Sturdivant RX. Applied logistic regression: John Wiley & Sons; 2013.

Cipriano Jr G, Neves LMT, Cipriano GFB, Chiappa GR, Borghi-Silva AJPicd. Cardiovascular disease prevention and implications for worksite health promotion programs in Brazil. 2014;56(5):493-500,

Mozaffarian D, Ludwig DSJJ. The 2015 US dietary guidelines: lifting the ban on total dietary fat. 2015;313(24):2421-2,

Miller MR, Shaw CA, Langrish JPJFc. From particles to patients: oxidative stress and the cardiovascular effects of air pollution. 2012;8(4):577-602,

Santoro V, Minardi V, Contoli B, Gallo R, Possenti V, Masocco MJAdISdS. Monitoring cardiovascular diseases and associated risk factors in the adult population to better orient prevention strategies in Italy. 2022;58(2):109-17,

Larsson SC, Burgess S, Mason AM, Michaëlsson KJCG, Medicine P. Alcohol consumption and cardiovascular disease: a Mendelian randomization study. 2020;13(3):e002814,

Biddinger KJ, Emdin CA, Haas ME, Wang M, Hindy G, Ellinor PT, et al. Association of habitual alcohol intake with risk of cardiovascular disease. 2022;5(3):e223849-e,

Lazarević AM, Nakatani S, Nešković AN, Marinković J, Yasumura Y, Stojičić D, et al. Early changes in left ventricular function in chronic asymptomatic alcoholics: relation to the duration of heavy drinking. 2000;35(6):1599-606,

López-Dequidt I, Martínez-Monzonis A, Peña-Gil C, González-Maestro A, González-Salvado V, Rodríguez-Castro E, et al. Results of a focused cardiac ultrasound program conducted by neurologists within a stroke care network with cardiac imaging units. 2022,

Strazzullo P, D'Elia L, Cairella G, Garbagnati F, Cappuccio FP, Scalfi LJS. Excess body weight and incidence of stroke: meta-analysis of prospective studies with 2 million participants. 2010;41(5):e418-e26,

Wan EYF, Fung WT, Schooling CM, Au Yeung SL, Kwok MK, Yu EYT, et al. Blood pressure and risk of cardiovascular disease in UK biobank: a mendelian randomization study. 2021;77(2):367-75,

Mongraw-Chaffin M, Bertoni AG, Golden SH, Mathioudakis N, Sears DD, Szklo M, et al. Association of low fasting glucose and HbA1c with cardiovascular disease and mortality: the MESA Study. 2019;3(5):892-901,

Hindy G, Engström G, Larsson SC, Traylor M, Markus HS, Melander O, et al. Role of blood lipids in the development of ischemic stroke and its subtypes: a Mendelian randomization study. 2018;49(4):820-7,

Yuan J, Zou X-R, Han S-P, Cheng H, Wang L, Wang J-W, et al. Prevalence and risk factors for cardiovascular disease among chronic kidney disease patients: results from the Chinese cohort study of chronic kidney disease (C-STRIDE). 2017;18(1):1-12.

Downloads

Published

01-12-2022

Issue

Section

Original Article

Categories

How to Cite

1.
Prevalence and Factors Associated with Coronary Artery Disease (CAD) and Its Associated Factors among People Aged 35 Years and Over in Thailand: A Cross-Sectional Analysis. IJPHAP [Internet]. 2022 Dec. 1 [cited 2024 Jun. 20];1(1). Available from: https://ijphap.com/index.php/home/article/view/16