Colorectal cancer survival in Thailand

Authors

  • Nattayakorn Monkhan Public Health Program, Faculty of Public Health Khon Kaen University, Thailand
  • Surachai Phimha Department of Public Health Administration, Health Promotion and Nutrition, Faculty of Public Health, Khon Kaen University, Thailand
  • Nakarin Prasit Department of Public Health Administration, Health Promotion and Nutrition, Faculty of Public Health, Khon Kaen University, Thailand
  • Nopparat Senahad Department of Public Health Administration, Health Promotion and Nutrition, Faculty of Public Health, Khon Kaen University, Thailand
  • Chanaporn Pinsuwan Public Health Program, Faculty of Public Health Khon Kaen University, Thailand

DOI:

https://doi.org/10.62992/ijphap.v2i3.36

Keywords:

Colorectal cancer, Survival rate, Patients in Thailand

Abstract

Background: Colorectal cancers are third among the world's most common cancers. Among the top five most common malignancies in Thailand, colorectal cancer primarily affects the elderly but affects persons of all ages as well. In addition, its incidence is rising yearly.

Objectives: This retrospective cohort study aimed to describe the survival rate of Colorectal cancer patients in Thailand.

Methods: The study used secondary data from the Ministry of Public Health between 2013 and 2020, a total of 57,321 cases were enrolled. Descriptive statistical analysis and inferential statistical analysis were performed by Cox regression analysis to observe survival rate estimate, Kaplan-Meier Survival estimate with 95% CI.    

Results: Among the total participants, 51.28% were male. Female survival rate was 9% higher than male Colorectal cancer patients (HR = 0.91, 95% CI: 0.86-0.94). The Colorectal cancer patients who were aged 61-70 years were more likely to pass away than patients aged £ 60 years (HR= 1.25, 95% CI:1.17- 1.34). Similarly, Colorectal cancer patients aged ≥70 years were more likely to have demise 1.58 times earlier than patients aged  £ 60 years (HR= 1.58, 95% CI: 1.49-1.68).

Conclusion: The survival rate of patients with colorectal cancer was significantly affected by gender. In addition, age was one of the variables which is also statistically significant that impacted on the colorectal cancer patient survival rate. Therefore, the formulation of screening policies for colorectal cancer in targeted populations, particularly in elderly should be established to support colorectal cancer prevention and reduce the risk to achieve a greater health impact among them.    

References

Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. 2015;136(5):E359-E86.

Organization WH. Colorectal 2021 2021 [Available from: https://gco.iarc.fr/overtime/en.

Siegel RL, Miller KD, Fedewa SA, Ahnen DJ, Meester RG, Barzi A, et al. Colorectal cancer statistics, 2017. 2017;67(3):177-93.

Analysing research on cancer prevention and survival [Internet]. World Cancer Research Fund. 2018. Available from: https://www.wcrf.org/wp-content/uploads/2021/02/Colorectal-cancer-report.pdf.

Murphy N, Moreno V, Hughes DJ, Vodicka L, Vodicka P, Aglago EK, et al. Lifestyle and dietary environmental factors in colorectal cancer susceptibility. 2019;69:2-9.

Keum N, Giovannucci EJNrG, hepatology. Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies. 2019;16(12):713-32.

Moghimi-Dehkordi B, Safaee A, Zali MRJSJoGOJotSGA. Comparison of colorectal and gastric cancer: survival and prognostic factors. 2009;15(1):18.

Institute NC. Colorectal 2021: National Cancer Institute; 2021 [Available from: https://gco.iarc.fr/overtime/en.%5bAccess.

Cancer Epidemiology and Prevention. Thun M, Linet MS, Cerhan JR, Haiman CA, Schottenfeld D, editors: Oxford University Press; 2017 21 Dec 2017.

National Economic and Social Development Plan [Internet]. 2020. Available from: https://www.nesdc.go.th/ewt_w3c/ewt_dl_link.php?nid=3784.

Institute NC. Cancer registry at hospital level 2018. Bangkok: New Normal Printing (Thailand), Institute NC; 2019.

Koo JH, Jalaludin B, Wong SK, Kneebone A, Connor SJ, Leong RWJOjotACoG, et al. Improved survival in young women with colorectal cancer. 2008;103(6):1488-95.

Sriplung H. Analysis of cancer data quality and cancer situation study and relationship relation to trends and distribution of risk factors from various sources. Health Systems Research Institute. 2010;7(1):1-118.

Watanabe T, Wu TT, Catalano PJ, Ueki T, Satriano R, Haller DG, et al. Molecular predictors of survival after adjuvant chemotherapy for colon cancer. The New England journal of medicine. 2001;344(16):1196-206.

Magaji BA, Moy FM, Roslani AC, Law CWJBc. Survival rates and predictors of survival among colorectal cancer patients in a Malaysian tertiary hospital. 2017;17(1):1-8.

Sharp L, McDevitt J, Brown C, Comber HJAp, therapeutics. Smoking at diagnosis significantly decreases 5‐year cancer‐specific survival in a population‐based cohort of 18 166 colon cancer patients. 2017;45(6):788-800.

Yameela M, Punyaphat C, Somkiat W. Factors associated with mortality in Colorectal Cancer Patient: A literature review. Journal of Community Public Health. 2020;6(3):1-21.

Boyle T, Fritschi L, Platell C, Heyworth JJBjoc. Lifestyle factors associated with survival after colorectal cancer diagnosis. 2013;109(3):814-22.

Joachim C, Godaert L, Dramé M, Véronique-Baudin J, Macni J, Smith-Ravin J, et al. Overall survival in elderly patients with colorectal cancer: A population-based study in the Caribbean. 2017;48:85-91.

Moamer S, Baghestani A, Pourhoseingholi MA, Hajizadeh N, Ahmadi F, Norouzinia MJG, et al. Evaluation of prognostic factors effect on survival time in patients with colorectal cancer, based on Weibull Competing-Risks Model. 2017;10(1):54.

Sharkas GF, Arqoub KH, Khader YS, Tarawneh MR, Nimri OF, Al-Zaghal MJ, et al. Colorectal cancer in Jordan: survival rate and its related factors. 2017;2017.

Dignam JJ, Ye Y, Colangelo L, Smith R, Mamounas EP, Wieand HS, et al. Prognosis after rectal cancer in blacks and whites participating in adjuvant therapy randomized trials. 2003;21(3):413-20.

Sudsawat Laohavinij M, Maneechavakajorn JJJMAT. Prognostic factors for survival in colorectal cancer patients. 2010;93(10):1156-66.

Society AC. American Cancer Society guideline for colorectal cancer screening. American Cancer Society Atlanta; 2018.

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Published

16-01-2024

How to Cite

1.
Monkhan N, Phimha S, Prasit N, Senahad N, Pinsuwan C. Colorectal cancer survival in Thailand. IJPHAP [Internet]. 2024 Jan. 16 [cited 2024 May 20];2(3):1-8. Available from: https://ijphap.com/index.php/home/article/view/36

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