Perinatal outcomes of COVID-19 infection during pregnancy at three central hospitals (Mahosot, Mittaphap, and Mother and Newborn Hospital), in Vientiane Capital, Lao PDR
DOI:
https://doi.org/10.62992/rmwwvw02Keywords:
COVID-19 during pregnancy, Lao PDRAbstract
Background: People who contract COVID-19 during pregnancy are at an increased risk for complications that can affect both their pregnancy and their developing baby.
Objective: This study aimed to identify perinatal outcomes of COVID-19 infection during pregnancy at three central hospitals (Mahosot, Mittaphap, and Mother and Newborn Hospital), in Vientiane Capital, Lao PDR.
Methods: This study was an analytical cross-sectional study. Purposive sampling was applied. The sample of this study consisted of 362 pregnant women who were infected with COVID-19 and gave birth in Mahosot, Mittaphap, and the Mother and New-born Hospital, Lao PDR as recorded in medical record books from 2019 to 2022. The data was collected using a data collection form designed by the researcher. SPSS version 25 was used to analyse the data. The multiple logistic regression was used to evaluate the association between the characteristics, their vaccinations, and perinatal outcomes.
Results: Among 362 pregnant women who were infected with COVID-19, the average age was 27.98 ± 5.71 years and 24.59% received COVID-19 vaccination. The percentage of babies with birth weight < 2500g was 14.60%. The percentage of babies with an APGAR score lower than 7 was 3.32%. The rate of babies admitted to the NICU was 4.14%. The fatal death rate was 1.38%. The antenatal care (ANC) visit was associated with baby weight after birth (Adjusted Odds Ratio (AOR) =1.04; 95% Confidence Interval (CI): 1.42,5.60). The body mass index (BMI) was associated with APGAR score (AOR=1.56; 95% CI 1.30,17.41).
Conclusion: There are some concerns regarding perinatal outcomes such as low birth weight, low APGAR score, babies being admitted to the NICU, and some instances of fatal death. The high frequency of ANC visit and well control of BMI was associated with the positive impact of perinatal outcomes.
References
Overton EE, Goffman D, Friedman AM. The Epidemiology of COVID-19 in Pregnancy. Clin Obstet Gynecol. 2022;65(1):110-22.
CDC: COVID-19 during pregnancy. Available at: https://www.cdc.gov/coronavirus/2019-ncov/cases-updates/special-populations/pregnancy-data-on-covid-19/what-cdc-is-doing.html. Date Cite: Oct 07, 2022
Pathirathna ML, Samarasekara BPP, Dasanayake TS, Saravanakumar P, Weerasekara I. Adverse Perinatal Outcomes in COVID-19 Infected Pregnant Women: A Systematic Review and Meta-Analysis. Healthcare (Basel). 2022;10(2).
Mother and newborn hospital Yearly report, 2022
Mahosot Hospital Yearly Report, 2022
OBGYN Department of Mittaphap hospital report, 2022
Smith V, Seo D, Warty R, Payne O, Salih M, Chin KL, et al. Maternal and neonatal outcomes associated with COVID-19 infection: A systematic review. PLOS ONE. 2020;15(6):e0234187.
Zaigham M, Andersson O. Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies. Acta Obstet Gynecol Scand. 2020 Jul;99(7):823-829. doi: 10.1111/aogs.13867. Epub 2020 Apr 20. PMID: 32259279; PMCID: PMC7262097.
Saban, A., Haleluya, N.L., Geva, Y. et al. Perinatal outcomes among pregnant patients with peripartum coronavirus disease 2019 infection. Arch Gynecol Obstet 310, 793–800 (2024). https://doi.org/10.1007/s00404-024-07536-9
McClymont E, Albert AY, Alton GD, et al. Association of SARS-CoV-2 Infection During Pregnancy With Maternal and Perinatal Outcomes. JAMA. 2022;327(20):1983–1991. doi:10.1001/jama.2022.5906
Simbar, M., Nazarpour, S., & Sheidaei, A. Evaluation of pregnancy outcomes in mothers with COVID-19 infection: a systematic review and meta-analysis. Journal of Obstetrics and Gynaecology, 43(1). 2023. https://doi.org/10.1080/01443615.2022.2162867
Deshmukh VL, Jadhav M, Yelikar K. Impact of HIGH BMI on Pregnancy: Maternal and Foetal Outcome. J Obstet Gynaecol India. 2016 Oct;66(Suppl 1):192-7. doi: 10.1007/s13224-015-0825-3. Epub 2016 Jan 13. PMID: 27651602; PMCID: PMC5016433.
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