Spatial association of socioeconomic factors and prevalence of Tuberculosis in Java Indonesia, 2021-2022

Authors

  • Mr. Alex Master of Public Health, Khon Kaen University, Khon Kaen, Thailand
  • Assoc. Prof. Dr. Kittipong Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand https://orcid.org/0000-0002-2734-0764

DOI:

https://doi.org/10.62992/wspjdd02

Keywords:

Prevalence, Socioeconomic factors, Spatial analysis, Tuberculosis

Abstract

Background: Tuberculosis (TB) remains one of the deadliest infectious diseases even in the aftermath of the COVID-19 pandemic. Although it is treatable and supported by national programs, Indonesia accounts for the second highest proportion of TB cases worldwide. Research on tuberculosis in Indonesia is generally limited to single-year studies in narrow areas at the regency level, restricting broader regional insights.

Objectives: This research aimed to identify the spatial relationship between socio-economic factors and tuberculosis prevalence in Java, Indonesia, for the years 2021 and 2022.

Methods: This cross-sectional study employed a geographical analytic approach using TB reported data across three provinces in Java, Indonesia to investigate the spread of disease and association in 2021-2022 from various sources.  Spatial autocorrelation analysis relies on Moran's I values to determine associations and Local Indicator of Spatial Association (LISA) to identify which regions in Java have high or low cluster values.

Results: The prevalence rate of tuberculosis in Java from 2021 to 2022 showed an increasing trend from an average of 145 to 148 per 100,000 inhabitants, with Tegal City consistently recording the highest prevalence. Boyolali Regency had the lowest rate in 2021, while Trenggalek had the lowest rate in 2022. TB hotspot detected in Bogor, Bandung, Karawang, Bekasi, Bekasi City, Cimahi City and Depok City. Meanwhile TB coldspots were consistently detected in Wonosobo, Magelang, Wonogiri, Magelang City, Surakarta City, Salatiga City, Pacitan, Ponorogo, Trenggalek, Tulungagung, Kediri, Madiun, Magetan, Ngawi, and Madiun City. Bivariate analysis indicated a positive spatial association between population density, per capita expenditure, night-time light (NTL), regional wage, and unemployment rate.

Conclusion: There existed spatial association between socioeconomic characteristics and tuberculosis prevalence in Java from 2021 to 2022, particularly in urbanized regions. This cartographic research should serve as a guideline for TB management in Java.

References

WHO. Global Tuberculosis Report 2023. Geneva: World Health Organization; 2023.

WHO. Global Tuberculosis Report 2022 Geneva: World Health Organization; 2022 [updated 2022. Available from: https://www.who.int/teams/global-tuberculosis-programme/tb-reports/global-tuberculosis-report-2022/tb-disease-burden/2-2-tb-mortality#refs.

Ministry of Health Indonesia. Data Dashboard on TB Conditions in Indonesia (Dashboard Data Kondisi TBC di Indonesia) Jakarta: Kementrian Kesehatan Republik Indonesia; 2023 [cited 2023 11/15]. Available from: https://tbindonesia.or.id/pustaka-tbc/dashboard/.

Kacholi G, Anasel M. Health at a glance 2023: OECD indicators. Paris: OECD Publishing; 2023.

Makgopa S, Cele LP, Mokgatle MM. Pre-Diagnosis Health Seeking Behaviors and Experiences Post-Diagnosis, among Men Diagnosed with Tuberculosis in a District of Gauteng Metropolitan City, South Africa: In-Depth Interviews. International Journal of Environmental Research and Public Health. 2022;19(20):13635.

Nizalova O, Shepotylo O. Impact of TB Epidemic on Worker and Firm Productivity: Regional Perspective from Ukraine. GLO Discussion Paper; 2023.

Mellander C, Lobo J, Stolarick K, Matheson Z. Night-Time Light Data: A Good Proxy Measure for Economic Activity? PLOS ONE. 2015;10(10):e0139779.

East Java Provincial Health Service. Health Profile of East Java (Profil Kesehatan Jawa Timur). Jawa Timur: Dinas Kesehatan Provinsi Jawa Timur; 2022.

West Java Provincial Health Service. Health Profile of West Java (Profil Kesehatan Jawa Barat)

Jawa Barat: Dinas Kesehatan Provinsi Jawa Barat; 2022.

Central Java Provincial Health Service. Health Profile of Central Java (Profil Kesehatan Jawa Tengah). Jawa Tengah: Dinas Kesehatan Provinsi Jawa Tengah; 2022.

Central Bureau of Statistics. National Labor Force Survey Booklet February 2023 (Booklet Survey Angkatan Kerja Nasional): BPS; 2023 Februaru 2023. 24 p.

Elvidge CD, Baugh K, Zhizhin M, Hsu FC, Ghosh T. VIIRS night-time lights. Remote Sensing of Night-time Light: Routledge; 2021. p. 6-25.

Kurt Menke G, Smith Jr R, Pirelli L, John Van Hoesen G. Mastering QGIS: Packt Publishing Ltd; 2016.

Anselin L, Syabri I, Kho Y. : An Introduction to Spatial Data Analysis. 2006;38(1):5-22.

Tadjoeddin Z, Mercer-Blackman V. Urbanization and labor productivity in Indonesia. Indonesia: Enhancing Productivity Through Quality Jobs. 2018:130-69.

Rao M, Johnson A. Impact of Population Density and Elevation on Tuberculosis Spread and Transmission in Maharashtra, India. Journal of Emerging Investigators. 2021;4:1-5.

Alene KA, Xu Z, Bai L, Yi H, Tan Y, Gray DJ, et al. Spatiotemporal Patterns of Tuberculosis in Hunan Province, China. 2021;18(13):6778.

Teibo TKA, Andrade RLP, Rosa RJ, Tavares RBV, Berra TZ, Arcêncio RA. Geo-spatial high-risk clusters of Tuberculosis in the global general population: a systematic review. BMC public health. 2023;23(1):1586.

Mahato RK, Htike KM, Koro AB, Yadav RK, Sharma V, Kafle A, et al. Spatial autocorrelation with environmental factors related to tuberculosis prevalence in Nepal, 2020–2023. Infectious Diseases of Poverty. 2025;14(1):15.

Yang D-l, Li W, Pan M-h, Su H-x, Li Y-n, Tang M-y, et al. Spatial analysis and influencing factors of pulmonary tuberculosis among students in Nanning, during 2012–2018. PLOS ONE. 2022;17(5):e0268472.

Onyechege DC, Mohamed Nor N, Wan Ngah Wan AS, Naseem NAM. Tuberculosis and its socioeconomic determinants in Nigeria: An empirical investigation using ARDL approach. European Journal of Environment and Public Health. 2023;7(1).

Zhang QY, Yang DM, Cao LQ, Liu JY, Tao NN, Li YF, et al. Association between economic development level and tuberculosis registered incidence in Shandong, China. BMC public health. 2020;20(1):1557.

Yadav J, John D, Allarakha S, Menon GR. Rising healthcare expenditure on tuberculosis: Can India achieve the End TB goal? Trop Med Int Health. 2021;26(10):1256-75.

Laksono AD, Wulandari RD, Rohmah N, Rukmini R, Tumaji T. Regional disparities in hospital utilisation in Indonesia: a cross-sectional analysis data from the 2018 Indonesian Basic Health Survey. BMJ open. 2023;13(1):e064532.

You Y, Chen Y, Fang W, Li X, Wang R, Liu J, et al. The association between sedentary behavior, exercise, and sleep disturbance: A mediation analysis of inflammatory biomarkers. Front Immunol. 2022;13:1080782.

Ramos AR, Wheaton AG, Johnson DA. Sleep Deprivation, Sleep Disorders, and Chronic Disease. Prev Chronic Dis. 2023;20:E77.

Ngo MD, Bartlett S, Ronacher K. Diabetes-Associated Susceptibility to Tuberculosis: Contribution of Hyperglycemia vs. Dyslipidemia. Microorganisms. 2021;9(11).

Abbas U, Masood KI, Khan A, Irfan M, Saifullah N, Jamil B, et al. Tuberculosis and diabetes mellitus: Relating immune impact of co-morbidity with challenges in disease management in high burden countries. Journal of clinical tuberculosis and other mycobacterial diseases. 2022;29:100343.

Datiko D, Hadgu A, Jerene D, Suarez PG. High urban tuberculosis case notification rates can be misleading: evidence from an urban setting in Ethiopia. BMC public health. 2020;20(1):302.

Nur K, Eni S, editors. Open Unemployment Rate in West Java in 2018 to 2021. Proceedings of the International Conference on Economics and Business Studies (ICOEBS-22-2); 2023 2023/10/04: Atlantis Press.

Anaam MS, Alrasheedy AA, Alsahali S, Alfadly SO, Aldhubhani AH. Rate and risk factors of recurrent tuberculosis in Yemen: a 5-year prospective study. Infect Dis. 2020;52(3):161-9.

Przybylski G, Dabrowska A, Pilaczyńska-Cemel M, Krawiecka D. Unemployment in TB patients - ten-year observation at regional center of pulmonology in Bydgoszcz, Poland. Medical science monitor : international medical journal of experimental and clinical research. 2014;20:2125-31.

Wanahari TA, Bakhriansyah M, Haryati H, Rudiansyah M, Isa M, Djallalluddin D, et al. Socioeconomic Determinants of Tuberculosis Cases in Indonesia, 2010–2013: An Ecological Study. Open Access Macedonian Journal of Medical Sciences. 2022;10(E):1489-95.

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Published

30-04-2026

How to Cite

1.
Spatial association of socioeconomic factors and prevalence of Tuberculosis in Java Indonesia, 2021-2022. IJPHAP [Internet]. 2026 Apr. 30 [cited 2026 Apr. 30];5(11):14-27. Available from: https://ijphap.com/index.php/home/article/view/144